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Clinical studies sponsored by the manufacturer have shown that bilastine 20 mg once daily is as efficacious as other nonsedating antihistamines in allergic rhinoconjunctivitis and chronic urticaria in individuals from 12 and 18 years of age, respectively.

Bilastine is efficacious in all nasal symptoms including obstruction and in eye symptoms.

The observations indicate that non-sedating antihistamines, as opposed to what has been thought previously, may be helpful in patients with allergic rhinitis in whom nasal obstruction is a major concern.

Once released, the histamine can react with local or widespread tissues through histamine receptors.Histamine, acting on H-antihistamines help against these effects, they work only if taken before contact with the allergen.In severe allergies, such as anaphylaxis or angioedema, these effects may be of life-threatening severity.Antihistamines are used in the treatment of allergic reactions, colds, hay fever, hives, and insect bites and stings.Some antihistamines may also be helpful in reducing anxiety, inducing sleep, or at preventing or treating motion sickness.

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